Comparative morphological characteristics of the proliferative activity and DNA content in the nuclei of cells of different lung cancer phenotypes

The choice of lung cancer treatment method directly depends on the diagnostisc and verification histological type tumor. Important diagnostic criteria are DNA accumulation index proliferation Ki-67. Materials methods. was assessed in 200 cases using a microspectrophotometric method. Ki-67 proliferative calculated immunohistochemical study material with antibodies to Ki-67, Cytokeratin 5/6, TTF-1, Chromogranin A, Synaptophysin, Keratin.Pan, CD56. Results. As degree tumor differentiation decreases, increase, serving as for aggressive behavior Conclusions. Correlation analysis revealed statistically significant relationship between (r = 0.987, p 0.05). obtained data may be useful diagnosis prognosis patients cancer.